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Single-Cell Analyses Identify Dysfunctional CD16(+) CD8 T Cells in Smokers

Tobacco smoke exposure contributes to the global burden of communicable and chronic diseases. To identify the immune cells affected by smoking, we use single-cell RNA sequencing on peripheral blood from smokers and nonsmokers. Transcriptomes reveal a subpopulation of FCGR3A (CD16)-expressing natural...

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Detalles Bibliográficos
Autores principales:	Martos, Suzanne N., Campbell, Michelle R., Lozoya, Oswaldo A., Wang, Xuting, Bennett, Brian D., Thompson, Isabel J.B., Wan, Ma, Pittman, Gary S., Bell, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644053/ https://www.ncbi.nlm.nih.gov/pubmed/33163982 http://dx.doi.org/10.1016/j.xcrm.2020.100054

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