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Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes

INTRODUCTION: Measure and monitor adverse events (AEs) following hip arthroplasty is challenging. The aim of this study was to create a model for measuring AEs after hip arthroplasty using administrative data, such as length of stay and readmissions, with equal or better precision than an ICD-code b...

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Autores principales: Magnéli, Martin, Unbeck, Maria, Rogmark, Cecilia, Sköldenberg, Olof, Gordon, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644076/
https://www.ncbi.nlm.nih.gov/pubmed/33152055
http://dx.doi.org/10.1371/journal.pone.0242008
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author Magnéli, Martin
Unbeck, Maria
Rogmark, Cecilia
Sköldenberg, Olof
Gordon, Max
author_facet Magnéli, Martin
Unbeck, Maria
Rogmark, Cecilia
Sköldenberg, Olof
Gordon, Max
author_sort Magnéli, Martin
collection PubMed
description INTRODUCTION: Measure and monitor adverse events (AEs) following hip arthroplasty is challenging. The aim of this study was to create a model for measuring AEs after hip arthroplasty using administrative data, such as length of stay and readmissions, with equal or better precision than an ICD-code based model. MATERIALS AND METHODS: This study included 1 998 patients operated with an acute or elective hip arthroplasty in a national multi-centre study. We collected AEs within 90 days following surgery with retrospective record review. Additional data came from the Swedish Hip Arthroplasty Register, the Swedish National Patient Register and the Swedish National Board of Health and Welfare. We made a 2:1 split of the data into a training and a holdout set. We used the training set to train different machine learning models to predict if a patient had sustained an AE or not. After training and cross-validation we tested the best performing model on the holdout-set. We compared the results with an established ICD-code based measure for AEs. RESULTS: The best performing model was a logistic regression model with four natural age splines. The variables included in the model were as follows: length of stay at the orthopaedic department, discharge to acute care, age, number of readmissions and ED visits. The sensitivity and specificity for the new model was 23 and 90% for AE within 30 days, compared with 5 and 94% for the ICD-code based model. For AEs within 90 days the sensitivity and specificity were 31% and 89% compared with 16% and 92% for the ICD-code based model. CONCLUSION: We conclude that a prediction model for AEs following hip arthroplasty surgery, relying on administrative data without ICD-codes is more accurate than a model based on ICD-codes.
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spelling pubmed-76440762020-11-16 Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes Magnéli, Martin Unbeck, Maria Rogmark, Cecilia Sköldenberg, Olof Gordon, Max PLoS One Research Article INTRODUCTION: Measure and monitor adverse events (AEs) following hip arthroplasty is challenging. The aim of this study was to create a model for measuring AEs after hip arthroplasty using administrative data, such as length of stay and readmissions, with equal or better precision than an ICD-code based model. MATERIALS AND METHODS: This study included 1 998 patients operated with an acute or elective hip arthroplasty in a national multi-centre study. We collected AEs within 90 days following surgery with retrospective record review. Additional data came from the Swedish Hip Arthroplasty Register, the Swedish National Patient Register and the Swedish National Board of Health and Welfare. We made a 2:1 split of the data into a training and a holdout set. We used the training set to train different machine learning models to predict if a patient had sustained an AE or not. After training and cross-validation we tested the best performing model on the holdout-set. We compared the results with an established ICD-code based measure for AEs. RESULTS: The best performing model was a logistic regression model with four natural age splines. The variables included in the model were as follows: length of stay at the orthopaedic department, discharge to acute care, age, number of readmissions and ED visits. The sensitivity and specificity for the new model was 23 and 90% for AE within 30 days, compared with 5 and 94% for the ICD-code based model. For AEs within 90 days the sensitivity and specificity were 31% and 89% compared with 16% and 92% for the ICD-code based model. CONCLUSION: We conclude that a prediction model for AEs following hip arthroplasty surgery, relying on administrative data without ICD-codes is more accurate than a model based on ICD-codes. Public Library of Science 2020-11-05 /pmc/articles/PMC7644076/ /pubmed/33152055 http://dx.doi.org/10.1371/journal.pone.0242008 Text en © 2020 Magnéli et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Magnéli, Martin
Unbeck, Maria
Rogmark, Cecilia
Sköldenberg, Olof
Gordon, Max
Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title_full Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title_fullStr Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title_full_unstemmed Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title_short Measuring adverse events following hip arthroplasty surgery using administrative data without relying on ICD-codes
title_sort measuring adverse events following hip arthroplasty surgery using administrative data without relying on icd-codes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644076/
https://www.ncbi.nlm.nih.gov/pubmed/33152055
http://dx.doi.org/10.1371/journal.pone.0242008
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