Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for “polygenic epistasis”

BACKGROUND: The majority of quantitative genetic models used to map complex traits assume that alleles have similar effects across all individuals. Significant evidence suggests, however, that epistatic interactions modulate the impact of many alleles. Nevertheless, identifying epistatic interaction...

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Detalles Bibliográficos
Autores principales: Rau, Christoph D., Gonzales, Natalia M., Bloom, Joshua S., Park, Danny, Ayroles, Julien, Palmer, Abraham A., Lusis, Aldons J., Zaitlen, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644088/
https://www.ncbi.nlm.nih.gov/pubmed/33104702
http://dx.doi.org/10.1371/journal.pgen.1009165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644088/
https://www.ncbi.nlm.nih.gov/pubmed/33104702
http://dx.doi.org/10.1371/journal.pgen.1009165

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