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Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions

Ryanodine receptors (RyR) are essential regulators of cellular calcium homeostasis and signaling. Vertebrate genomes contain multiple RyR gene isoforms, expressed in different tissues and executing different functions. In contrast, invertebrate genomes contain a single RyR-encoding gene and it has l...

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Detalles Bibliográficos
Autores principales: Marques, Filipe, Thapliyal, Saurabh, Javer, Avelino, Shrestha, Priyanka, Brown, André E. X., Glauser, Dominique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644089/
https://www.ncbi.nlm.nih.gov/pubmed/33104696
http://dx.doi.org/10.1371/journal.pgen.1009102