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Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Interferons (IFNs) are cytokines that are central to the host defence against viruses and other microorganisms. If not properly regulated, IFNs may contribute to the pathogenesis of inflammatory autoimmune, or infectious diseases. To identify genetic polymorphisms regulating the IFN system we perfor...

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Detalles Bibliográficos
Autores principales:	Lundtoft, Christian, Pucholt, Pascal, Imgenberg-Kreuz, Juliana, Carlsson-Almlöf, Jonas, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Nordmark, Gunnel, Sandling, Johanna K., Kockum, Ingrid, Olsson, Tomas, Rönnblom, Lars, Hagberg, Niklas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644105/ https://www.ncbi.nlm.nih.gov/pubmed/33104735 http://dx.doi.org/10.1371/journal.pgen.1009199

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