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Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report

SARS-CoV-2 (COVID-19) is well known to have extrapulmonary manifestations, including acute renal failure. While radiologic findings of COVID-19 pulmonary-involvement have been described, renal findings associated with COVID-19 have not. We present a case of a 38-year-old Afro-Caribbean female diagno...

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Autores principales: Tancredi, Tyler, DeWaters, Ami, McGillen, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644181/
https://www.ncbi.nlm.nih.gov/pubmed/33171364
http://dx.doi.org/10.1016/j.clinimag.2020.11.011
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author Tancredi, Tyler
DeWaters, Ami
McGillen, Kathryn L.
author_facet Tancredi, Tyler
DeWaters, Ami
McGillen, Kathryn L.
author_sort Tancredi, Tyler
collection PubMed
description SARS-CoV-2 (COVID-19) is well known to have extrapulmonary manifestations, including acute renal failure. While radiologic findings of COVID-19 pulmonary-involvement have been described, renal findings associated with COVID-19 have not. We present a case of a 38-year-old Afro-Caribbean female diagnosed with COVID-19 whose renal ultrasound showed increased parenchymal echogenicity, decreased global color Doppler signal with elevated resistive indices, but no large vessel thrombi. Non-targeted renal biopsy demonstrated collapsing focal segmental glomerulosclerosis (FSGS), likely secondary to COVID-19 infection, which may be a specific manifestation of this disease that has been predominantly reported in Black patients. We report several findings on renal ultrasound with duplex Doppler not previously associated with COVID, specifically with FSGS, which in conjunction can be useful to both the radiologist and the clinician, potentially pointing them in the direction of this diagnosis and early treatment.
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spelling pubmed-76441812020-11-06 Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report Tancredi, Tyler DeWaters, Ami McGillen, Kathryn L. Clin Imaging Body Imaging SARS-CoV-2 (COVID-19) is well known to have extrapulmonary manifestations, including acute renal failure. While radiologic findings of COVID-19 pulmonary-involvement have been described, renal findings associated with COVID-19 have not. We present a case of a 38-year-old Afro-Caribbean female diagnosed with COVID-19 whose renal ultrasound showed increased parenchymal echogenicity, decreased global color Doppler signal with elevated resistive indices, but no large vessel thrombi. Non-targeted renal biopsy demonstrated collapsing focal segmental glomerulosclerosis (FSGS), likely secondary to COVID-19 infection, which may be a specific manifestation of this disease that has been predominantly reported in Black patients. We report several findings on renal ultrasound with duplex Doppler not previously associated with COVID, specifically with FSGS, which in conjunction can be useful to both the radiologist and the clinician, potentially pointing them in the direction of this diagnosis and early treatment. Elsevier Inc. 2021-03 2020-11-05 /pmc/articles/PMC7644181/ /pubmed/33171364 http://dx.doi.org/10.1016/j.clinimag.2020.11.011 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Body Imaging
Tancredi, Tyler
DeWaters, Ami
McGillen, Kathryn L.
Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title_full Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title_fullStr Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title_full_unstemmed Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title_short Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
title_sort renal ultrasound findings secondary to covid-19 related collapsing focal segmental glomerulosclerosis – a case report
topic Body Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644181/
https://www.ncbi.nlm.nih.gov/pubmed/33171364
http://dx.doi.org/10.1016/j.clinimag.2020.11.011
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