RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development

The characterization of prostate epithelial hierarchy and lineage heterogeneity is critical to understand its regenerative properties and malignancies. Here, we report that the transcription factor RUNX1 marks a specific subpopulation of proximal luminal cells (PLCs), enriched in the periurethral re...

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Detalles Bibliográficos
Autores principales: Mevel, Renaud, Steiner, Ivana, Mason, Susan, Galbraith, Laura CA, Patel, Rahima, Fadlullah, Muhammad ZH, Ahmad, Imran, Leung, Hing Y, Oliveira, Pedro, Blyth, Karen, Baena, Esther, Lacaud, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644213/
https://www.ncbi.nlm.nih.gov/pubmed/33025905
http://dx.doi.org/10.7554/eLife.60225

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