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Localized Lymph Node Light Chain Amyloidosis
The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644486/ https://www.ncbi.nlm.nih.gov/pubmed/32611959 http://dx.doi.org/10.2169/internalmedicine.4651-20 |
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author | Yamamoto, Akira Fujii, Nobuharu Obika, Mikako Yamashita, Taro Otsuka, Fumio |
author_facet | Yamamoto, Akira Fujii, Nobuharu Obika, Mikako Yamashita, Taro Otsuka, Fumio |
author_sort | Yamamoto, Akira |
collection | PubMed |
description | The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis. |
format | Online Article Text |
id | pubmed-7644486 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-76444862020-11-13 Localized Lymph Node Light Chain Amyloidosis Yamamoto, Akira Fujii, Nobuharu Obika, Mikako Yamashita, Taro Otsuka, Fumio Intern Med Case Report The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis. The Japanese Society of Internal Medicine 2020-06-30 2020-10-01 /pmc/articles/PMC7644486/ /pubmed/32611959 http://dx.doi.org/10.2169/internalmedicine.4651-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Yamamoto, Akira Fujii, Nobuharu Obika, Mikako Yamashita, Taro Otsuka, Fumio Localized Lymph Node Light Chain Amyloidosis |
title | Localized Lymph Node Light Chain Amyloidosis |
title_full | Localized Lymph Node Light Chain Amyloidosis |
title_fullStr | Localized Lymph Node Light Chain Amyloidosis |
title_full_unstemmed | Localized Lymph Node Light Chain Amyloidosis |
title_short | Localized Lymph Node Light Chain Amyloidosis |
title_sort | localized lymph node light chain amyloidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644486/ https://www.ncbi.nlm.nih.gov/pubmed/32611959 http://dx.doi.org/10.2169/internalmedicine.4651-20 |
work_keys_str_mv | AT yamamotoakira localizedlymphnodelightchainamyloidosis AT fujiinobuharu localizedlymphnodelightchainamyloidosis AT obikamikako localizedlymphnodelightchainamyloidosis AT yamashitataro localizedlymphnodelightchainamyloidosis AT otsukafumio localizedlymphnodelightchainamyloidosis |