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Localized Lymph Node Light Chain Amyloidosis

The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has b...

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Autores principales: Yamamoto, Akira, Fujii, Nobuharu, Obika, Mikako, Yamashita, Taro, Otsuka, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644486/
https://www.ncbi.nlm.nih.gov/pubmed/32611959
http://dx.doi.org/10.2169/internalmedicine.4651-20
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author Yamamoto, Akira
Fujii, Nobuharu
Obika, Mikako
Yamashita, Taro
Otsuka, Fumio
author_facet Yamamoto, Akira
Fujii, Nobuharu
Obika, Mikako
Yamashita, Taro
Otsuka, Fumio
author_sort Yamamoto, Akira
collection PubMed
description The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.
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spelling pubmed-76444862020-11-13 Localized Lymph Node Light Chain Amyloidosis Yamamoto, Akira Fujii, Nobuharu Obika, Mikako Yamashita, Taro Otsuka, Fumio Intern Med Case Report The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis. The Japanese Society of Internal Medicine 2020-06-30 2020-10-01 /pmc/articles/PMC7644486/ /pubmed/32611959 http://dx.doi.org/10.2169/internalmedicine.4651-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamamoto, Akira
Fujii, Nobuharu
Obika, Mikako
Yamashita, Taro
Otsuka, Fumio
Localized Lymph Node Light Chain Amyloidosis
title Localized Lymph Node Light Chain Amyloidosis
title_full Localized Lymph Node Light Chain Amyloidosis
title_fullStr Localized Lymph Node Light Chain Amyloidosis
title_full_unstemmed Localized Lymph Node Light Chain Amyloidosis
title_short Localized Lymph Node Light Chain Amyloidosis
title_sort localized lymph node light chain amyloidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644486/
https://www.ncbi.nlm.nih.gov/pubmed/32611959
http://dx.doi.org/10.2169/internalmedicine.4651-20
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