Low-dose Selective Arterial Calcium Stimulation Test for Localizing Insulinoma: A Single-center Experience of Five Consecutive Cases

The selective arterial calcium stimulation test (SACST) is one of the most useful localization tests for insulinoma but can cause false-positive and/or unexpected multi arterial positive results that hamper clinical decisions. There are also several adverse effects, such as nausea and hypoglycemia,...

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Detalles Bibliográficos
Autores principales: Hatoko, Tomonobu, Murakami, Takaaki, Sone, Masakatsu, Yabe, Daisuke, Masui, Toshihiko, Nakamoto, Yuji, Furuta, Akihiro, Uza, Norimitsu, Kodama, Yuzo, Harada, Norio, Ogura, Masahito, Yasoda, Akihiro, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644493/
https://www.ncbi.nlm.nih.gov/pubmed/32611954
http://dx.doi.org/10.2169/internalmedicine.4396-20
Descripción
Sumario:The selective arterial calcium stimulation test (SACST) is one of the most useful localization tests for insulinoma but can cause false-positive and/or unexpected multi arterial positive results that hamper clinical decisions. There are also several adverse effects, such as nausea and hypoglycemia, at the conventional dose (0.025 mEq/kg) of calcium injection. We herein report five consecutive insulinoma cases in which low-dose (0.005-0.007 mEq/kg) calcium injection for SACST led to successful insulinoma localization. No adverse effects of SACST were observed. In conclusion, a low-dose SACST can be a favorable option as an insulinoma localization test in terms of accuracy and safety.

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