Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion

An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of poly...

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Detalles Bibliográficos
Autores principales: Kusaba, Yusaku, Izumi, Shinyu, Takasaki, Jin, Suzuki, Manabu, Katagiri, Daisuke, Katsuno, Takashi, Matsumoto, Shuichiro, Sakamoto, Keita, Hashimoto, Masao, Ohmagari, Norio, Katano, Harutaka, Suzuki, Tadaki, Hojo, Masayuki, Sugiyama, Haruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644505/
https://www.ncbi.nlm.nih.gov/pubmed/32863364
http://dx.doi.org/10.2169/internalmedicine.5413-20
Descripción
Sumario:An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.

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