Cargando…

Chemogenetic selective manipulation of nucleus accumbens medium spiny neurons bidirectionally controls alcohol intake in male and female rats

The nucleus accumbens (NAc), considered the hub of reward circuitry, is comprised of two medium spiny neuron (MSN) subtypes that are classified by their enrichment of dopamine 1 (D1) or 2 (D2) receptors. While reports indicate that alcohol increases excitatory neurotransmission exclusively on NAc D1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strong, C. E., Hagarty, D. P., Brea Guerrero, A., Schoepfer, K. J., Cajuste, S. M., Kabbaj, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644642/ https://www.ncbi.nlm.nih.gov/pubmed/33154463 http://dx.doi.org/10.1038/s41598-020-76183-2

Ejemplares similares

Presence of Inhibitory Glycinergic Transmission in Medium Spiny Neurons in the Nucleus Accumbens
por: Muñoz, Braulio, et al.
Publicado: (2018)

Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens
por: Bessa, J M, et al.
Publicado: (2013)

Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion
por: Soares-Cunha, Carina, et al.
Publicado: (2019)

Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density
por: Strong, Caroline E., et al.
Publicado: (2019)

Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens
por: Gangarossa, Giuseppe, et al.
Publicado: (2013)

Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons
por: Kronman, Hope, et al.
Publicado: (2019)

Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
por: García-González, Diego, et al.
Publicado: (2020)

Binge Alcohol Drinking Alters Synaptic Processing of Executive and Emotional Information in Core Nucleus Accumbens Medium Spiny Neurons
por: Kolpakova, Jenya, et al.
Publicado: (2021)

Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro
por: Geldwert, Daron, et al.
Publicado: (2006)

The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens
por: Baimel, Corey, et al.
Publicado: (2019)

Correction: Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
por: García-González, Diego, et al.
Publicado: (2021)

Chemogenetic Stimulation and Silencing of the Insula, Amygdala, Nucleus Accumbens, and Their Connections Differentially Modulate Alcohol Drinking in Rats
por: Haaranen, Mia, et al.
Publicado: (2020)

Activation of histamine type 2 receptors enhances intrinsic excitability of medium spiny neurons in the nucleus accumbens
por: Aceto, Giuseppe, et al.
Publicado: (2022)

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens
por: Mizuno, Takeo, et al.
Publicado: (2007)

Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens
por: Ma, Yao-Ying, et al.
Publicado: (2013)

Involvement of nucleus accumbens D2–medium spiny neurons projecting to the ventral pallidum in anxiety-like behaviour
por: Correia, Raquel, et al.
Publicado: (2023)

Excitation of medium spiny neurons by ‘inhibitory’ ultrapotent chemogenetics via shifts in chloride reversal potential
por: Gantz, Stephanie C, et al.
Publicado: (2021)

Binge alcohol drinking alters the differential control of cholinergic interneurons over nucleus accumbens D1 and D2 medium spiny neurons
por: Kolpakova, Jenya, et al.
Publicado: (2022)

Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents
por: Steephen, John, et al.
Publicado: (2007)

Prolonged Consumption of Sucrose in a Binge-Like Manner, Alters the Morphology of Medium Spiny Neurons in the Nucleus Accumbens Shell
por: Klenowski, Paul M., et al.
Publicado: (2016)

The estrous cycle and 17β‐estradiol modulate the electrophysiological properties of rat nucleus accumbens core medium spiny neurons
por: Krentzel, Amanda A., et al.
Publicado: (2022)

Subregional Differences in Medium Spiny Neuron Intrinsic Excitability Properties between Nucleus Accumbens Core and Shell in Male Rats
por: Maria-Rios, Cristina E., et al.
Publicado: (2023)

Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine
por: Browne, Caleb J, et al.
Publicado: (2023)

Nucleus Accumbens Chemogenetic Inhibition Suppresses Amphetamine-Induced Ultrasonic Vocalizations in Male and Female Rats
por: Lawson, Kate A., et al.
Publicado: (2021)

Chronic Chemogenetic Stimulation of the Nucleus Accumbens Produces Lasting Reductions in Binge Drinking and Ameliorates Alcohol-Related Morphological and Transcriptional Changes
por: Pozhidayeva, Dar’ya Y., et al.
Publicado: (2020)

Long-Lasting Alterations in Membrane Properties, K(+) Currents, and Glutamatergic Synaptic Currents of Nucleus Accumbens Medium Spiny Neurons in a Rat Model of Alcohol Dependence
por: Marty, Vincent N., et al.
Publicado: (2012)

No Evidence for Sex Differences in the Electrophysiological Properties and Excitatory Synaptic Input onto Nucleus Accumbens Shell Medium Spiny Neurons123
por: Willett, Jaime A., et al.
Publicado: (2016)

Sex-Dependent Ketamine Addiction-Like Behavior Profile Following Exposure to Chronic Mild Stress
por: Wright, Katherine N., et al.
Publicado: (2019)

Three-dimensional organization of dendrites and local axon collaterals of shell and core medium-sized spiny projection neurons of the rat nucleus accumbens
por: van Dongen, Yvette C., et al.
Publicado: (2008)

Synaptic Connectivity in Medium Spiny Neurons of the Nucleus Accumbens: A Sex-Dependent Mechanism Underlying Apathy in the HIV-1 Transgenic Rat
por: McLaurin, Kristen A., et al.
Publicado: (2018)

The Sodium Channel β4 Auxiliary Subunit Selectively Controls Long-Term Depression in Core Nucleus Accumbens Medium Spiny Neurons
por: Ji, Xincai, et al.
Publicado: (2017)

Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens
por: McDevitt, Dillon S., et al.
Publicado: (2019)

Effects of the estrous cycle and ovarian hormones on cue-triggered motivation and intrinsic excitability of medium spiny neurons in the Nucleus Accumbens core of female rats
por: Alonso-Caraballo, Yanaira, et al.
Publicado: (2019)

AKAP150 from nucleus accumbens dopamine D1 and D2 receptor-expressing medium spiny neurons regulates morphine withdrawal
por: Bai, Xiaohui, et al.
Publicado: (2023)

S36. DIFFERENTIAL ENCODING OF SENSITIZATION AND CROSS SENSITIZATION TO PSYCHOSTIMULANTS AND ANTIPSYCHOTICS IN NUCLEUS ACCUMBENS D1- AND D2- RECEPTOR EXPRESSING MEDIUM SPINY NEURONS
por: Amato, Davide, et al.
Publicado: (2018)

Whole Genome DNA Methylation Profiling of D2 Medium Spiny Neurons in Mouse Nucleus Accumbens Using Two Independent Library Preparation Methods
por: Li, Yuxiang, et al.
Publicado: (2022)

The effects of ninjin’yoeito on the electrophysiological properties of dopamine neurons in the ventral tegmental area/substantia nigra pars compacta and medium spiny neurons in the nucleus accumbens
por: Imai, Ryota, et al.
Publicado: (2022)

Drug-primed reinstatement of cocaine seeking in mice: increased excitability of mediumsized spiny neurons in the nucleus accumbens
por: Ma, Yao-Ying, et al.
Publicado: (2013)

Signaling from the Cytoplasm to the Nucleus in Striatal Medium-Sized Spiny Neurons
por: Matamales, Miriam, et al.
Publicado: (2011)

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
por: Gross, Kellie S., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p9jecd1v97mv7f4gu9dfi9q9po