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Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses
Vaccines based on live attenuated viruses often induce broad, multifaceted immune responses. However, they also usually sacrifice immunogenicity for attenuation. It is particularly difficult to elicit an effective vaccine for herpesviruses due to an armament of immune evasion genes and a latent phas...
Autores principales: | Brar, Gurpreet, Farhat, Nisar A., Sukhina, Alisa, Lam, Alex K., Kim, Yong Hoon, Hsu, Tiffany, Tong, Leming, Lin, Wai Wai, Ware, Carl F., Blackman, Marcia A., Sun, Ren, Wu, Ting-Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644650/ https://www.ncbi.nlm.nih.gov/pubmed/33298958 http://dx.doi.org/10.1038/s41541-020-00251-x |
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