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Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses

Vaccines based on live attenuated viruses often induce broad, multifaceted immune responses. However, they also usually sacrifice immunogenicity for attenuation. It is particularly difficult to elicit an effective vaccine for herpesviruses due to an armament of immune evasion genes and a latent phas...

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Detalles Bibliográficos
Autores principales: Brar, Gurpreet, Farhat, Nisar A., Sukhina, Alisa, Lam, Alex K., Kim, Yong Hoon, Hsu, Tiffany, Tong, Leming, Lin, Wai Wai, Ware, Carl F., Blackman, Marcia A., Sun, Ren, Wu, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644650/
https://www.ncbi.nlm.nih.gov/pubmed/33298958
http://dx.doi.org/10.1038/s41541-020-00251-x

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