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Single-gene imaging links genome topology, promoter-enhancer communication and transcription control

Transcription activation by distal enhancers is essential for cell-fate specification and maintenance of cellular identities. How long-range gene regulation is physically achieved, especially within complex regulatory landscapes of non-binary enhancer-promoter configurations, remains elusive. Recent...

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Detalles Bibliográficos
Autores principales: Li, Jieru, Hsu, Angela, Hua, Yujing, Wang, Guanshi, Cheng, Lingling, Ochiai, Hiroshi, Yamamoto, Takashi, Pertsinidis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644657/
https://www.ncbi.nlm.nih.gov/pubmed/32958948
http://dx.doi.org/10.1038/s41594-020-0493-6