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A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats
Antibody phage display is a powerful platform for discovery of clinically applicable high affinity monoclonal antibodies against a broad range of targets. Libraries generated from immunized animals offer the advantage of in vivo affinity-maturation of V regions prior to library generation. Despite a...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644676/ https://www.ncbi.nlm.nih.gov/pubmed/33154441 http://dx.doi.org/10.1038/s41598-020-76069-3 |