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Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation

PURPOSE: To report the surgical management of extensive epibulbar dermoids with autologous oral mucous membrane transplantation. OBSERVATIONS: While rare, extensive dermoids that encroach upon the visual axis carry a poor prognosis. We report the case of a 7-week old premature male infant who presen...

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Autores principales: Umfress, Allison C., Mawn, Louise A., Joos, Karen M., Donahue, Sean P., Schmitt, Allyson D., Shieh, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644850/
https://www.ncbi.nlm.nih.gov/pubmed/33195879
http://dx.doi.org/10.1016/j.ajoc.2020.100982
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author Umfress, Allison C.
Mawn, Louise A.
Joos, Karen M.
Donahue, Sean P.
Schmitt, Allyson D.
Shieh, Christine
author_facet Umfress, Allison C.
Mawn, Louise A.
Joos, Karen M.
Donahue, Sean P.
Schmitt, Allyson D.
Shieh, Christine
author_sort Umfress, Allison C.
collection PubMed
description PURPOSE: To report the surgical management of extensive epibulbar dermoids with autologous oral mucous membrane transplantation. OBSERVATIONS: While rare, extensive dermoids that encroach upon the visual axis carry a poor prognosis. We report the case of a 7-week old premature male infant who presented with large bilateral epibulbar dermoids obscuring the visual axis. He was treated first with sequential bilateral optical iridectomies under the clearest corneal areas, followed several months later by sequential dermoid excision and amniotic membrane transplantation in each eye. He subsequently underwent autologous “simple” oral mucosal epithelial transplantation (SOMET) as well as strabismus surgery. Conclusions and Importance: Here we present the first case, to the best of our knowledge, of the use of SOMET in managing post-operative pseudopterygium following dermoid excision. To our knowledge it is the also the first application of this technique in a young pediatric patient. A good clinical outcome may be achieved with SOMET, which may offer a minimally invasive alternative to other traditional modalities.
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spelling pubmed-76448502020-11-13 Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation Umfress, Allison C. Mawn, Louise A. Joos, Karen M. Donahue, Sean P. Schmitt, Allyson D. Shieh, Christine Am J Ophthalmol Case Rep Case Report PURPOSE: To report the surgical management of extensive epibulbar dermoids with autologous oral mucous membrane transplantation. OBSERVATIONS: While rare, extensive dermoids that encroach upon the visual axis carry a poor prognosis. We report the case of a 7-week old premature male infant who presented with large bilateral epibulbar dermoids obscuring the visual axis. He was treated first with sequential bilateral optical iridectomies under the clearest corneal areas, followed several months later by sequential dermoid excision and amniotic membrane transplantation in each eye. He subsequently underwent autologous “simple” oral mucosal epithelial transplantation (SOMET) as well as strabismus surgery. Conclusions and Importance: Here we present the first case, to the best of our knowledge, of the use of SOMET in managing post-operative pseudopterygium following dermoid excision. To our knowledge it is the also the first application of this technique in a young pediatric patient. A good clinical outcome may be achieved with SOMET, which may offer a minimally invasive alternative to other traditional modalities. Elsevier 2020-10-28 /pmc/articles/PMC7644850/ /pubmed/33195879 http://dx.doi.org/10.1016/j.ajoc.2020.100982 Text en © 2020 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Umfress, Allison C.
Mawn, Louise A.
Joos, Karen M.
Donahue, Sean P.
Schmitt, Allyson D.
Shieh, Christine
Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title_full Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title_fullStr Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title_full_unstemmed Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title_short Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
title_sort surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644850/
https://www.ncbi.nlm.nih.gov/pubmed/33195879
http://dx.doi.org/10.1016/j.ajoc.2020.100982
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