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Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic

In this study, we analyzed full-length SARS-CoV-2 genomes from multiple countries to determine early trends in the evolutionary dynamics of the novel COVID-19 pandemic. Results indicated SARS-CoV-2 evolved early into at least three phylogenetic groups, characterized by positive selection at specific...

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Detalles Bibliográficos
Autores principales: Velazquez-Salinas, Lauro, Zarate, Selene, Eberl, Samantha, Gladue, Douglas P., Novella, Isabel, Borca, Manuel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644918/
https://www.ncbi.nlm.nih.gov/pubmed/33193132
http://dx.doi.org/10.3389/fmicb.2020.550674