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The Oscillation Amplitude, Not the Frequency of Cytosolic Calcium, Regulates Apoptosis Induction
Although a rising concentration of cytosolic Ca(2+) has long been recognized as an essential signal for apoptosis, the dynamical mechanisms by which Ca(2+) regulates apoptosis are not clear yet. To address this, we constructed a computational model that integrates known biochemical reactions and can...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644924/ https://www.ncbi.nlm.nih.gov/pubmed/33196017 http://dx.doi.org/10.1016/j.isci.2020.101671 |