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Pyruvate Kinase M2 Coordinates Metabolism Switch between Glycolysis and Glutaminolysis in Cancer Cells

Cancer cells alter their nutrition metabolism to cope the stressful environment. One important metabolism adjustment is that cancer cells activate glutaminolysis in response to the reduced carbon from glucose entering into the TCA cycle due to inactivation of several enzymes in glycolysis. An import...

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Detalles Bibliográficos
Autores principales: Li, Liangwei, Peng, Guangda, Liu, Xiaowei, Zhang, Yinwei, Han, Hongwei, Liu, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644948/
https://www.ncbi.nlm.nih.gov/pubmed/33196019
http://dx.doi.org/10.1016/j.isci.2020.101684