Cargando…

Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats

OBJECTIVE: To investigate the effects of ketogenic metabolism on macrophage polarization, inflammation inhibition, and function recovery after acute spinal cord injury (SCI) in rats. METHODS: Sixty-four adult male Sprague–Dawley rats were randomly and equally divided into sham, standard diet (SD), k...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Junyu, Huang, Zucheng, Liu, Junhao, Huang, Zhiping, Liu, Yapu, Liu, Qi, Yang, Zhou, Li, Ruoyao, Wu, Xiuhua, Shi, Zhe, Zhu, Qingan, Wu, Xiaoliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645058/ https://www.ncbi.nlm.nih.gov/pubmed/33192269 http://dx.doi.org/10.3389/fnins.2020.583611

Ejemplares similares

Trihydroxyethyl Rutin Provides Neuroprotection in Rats With Cervical Spinal Cord Hemi-Contusion
por: Liu, Yapu, et al.
Publicado: (2021)

Comparison of Three-Dimensional Micro-CT Angiography of Cervical Spinal Cord between Two Contrast Agents
por: Liu, Yapu, et al.
Publicado: (2019)

Rapamycin Preserves Neural Tissue, Promotes Schwann Cell Myelination and Reduces Glial Scar Formation After Hemi-Contusion Spinal Cord Injury in Mice
por: Liu, Junhao, et al.
Publicado: (2021)

Cervical spinal instability causes vertebral microarchitecture change and vertebral endplate lesion in rats
por: Liu, Qi, et al.
Publicado: (2019)

Comparison of the anatomical morphology of cervical vertebrae between humans and macaques: related to a spinal cord injury model
por: Liu, Junhao, et al.
Publicado: (2020)

Unilateral cervical spinal cord injury induces bone loss and metabolic changes in non-human primates (Macaca fascicularis)
por: Wu, Xiuhua, et al.
Publicado: (2021)

Bone loss and biomechanical reduction of appendicular and axial bones under ketogenic diet in rats
por: Ding, Jianyang, et al.
Publicado: (2019)

Feasibility of Anterior Fixation with Single Screw for Odontoid Fractures in Pediatrics: A Computed Tomographic Study
por: Lin, Junyu, et al.
Publicado: (2023)

Bone microstructure and metabolism changes under the combined intervention of ketogenic diet with intermittent fasting: an in vivo study of rats
por: Xu, Xiaolin, et al.
Publicado: (2019)

β hydroxybutyrate levels in serum and cerebrospinal fluid under ketone body metabolism in rats
por: Wang, Xiaomeng, et al.
Publicado: (2017)

Neuroprotective effects of a ketogenic diet in combination with exogenous ketone salts following acute spinal cord injury
por: Tan, Bo-Tao, et al.
Publicado: (2020)

The risk of translaminar screw fixation to the transverse foramen of the lower cervical spine: a computed tomography study
por: Kong, Ganggang, et al.
Publicado: (2017)

Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury
por: Fan, Hong, et al.
Publicado: (2020)

Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia
por: Fan, Hong, et al.
Publicado: (2021)

Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits
por: Liu, Bingbing, et al.
Publicado: (2015)

Ipsilateral Fixation and Reconstruction of the Cervical Spine after Resection of a Dumbbell Tumor Via a Unilateral Posterior Approach: A Case Report and Biomechanical Study
por: Zeng, Yongqiang, et al.
Publicado: (2023)

Macrophage polarization in diabetic wound healing
por: Wu, Xingqian, et al.
Publicado: (2022)

Clival Screw Placement in Patient with atlas assimilation: A CT-based feasibility study
por: Ji, Wei, et al.
Publicado: (2016)

Mechanism of mesenchymal stem cells in spinal cord injury repair through macrophage polarization
por: An, Nan, et al.
Publicado: (2021)

Neuroprotective effects of electroacupuncture on early- and late-stage spinal cord injury
por: Wu, Min-fei, et al.
Publicado: (2015)

Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats
por: Fan, Hong, et al.
Publicado: (2019)

Neuroprotective effects of interleukin 10 in spinal cord injury
por: Li, Juan, et al.
Publicado: (2023)

Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury
por: Zhang, Chuanjie, et al.
Publicado: (2021)

Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation
por: Zeng, Yuzhe, et al.
Publicado: (2018)

Neuroprotection and its molecular mechanism following spinal cord injury☆
por: Liu, Nai-Kui, et al.
Publicado: (2012)

Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms
por: Yang, Huajun, et al.
Publicado: (2019)

Ketone body β-hydroxybutyrate ameliorates colitis by promoting M2 macrophage polarization through the STAT6-dependent signaling pathway
por: Huang, Chongyang, et al.
Publicado: (2022)

Feasibility of C2 Vertebra Screws Placement in Patient With Occipitalization of Atlas: A Tomographic Study
por: Ji, Wei, et al.
Publicado: (2015)

Polarized Macrophages Have Distinct Roles in the Differentiation and Migration of Embryonic Spinal-cord-derived Neural Stem Cells After Grafting to Injured Sites of Spinal Cord
por: Zhang, Kun, et al.
Publicado: (2015)

Advances in the research of the role of macrophage/microglia polarization-mediated inflammatory response in spinal cord injury
por: Fu, Sheng-Ping, et al.
Publicado: (2022)

Neuroprotection by diarylpropionitrile in mice with spinal cord injury
por: Suwanna, Nirut, et al.
Publicado: (2014)

Neuroprotective role of Noggin in spinal cord injury
por: Al-Sammarraie, Nadia, et al.
Publicado: (2022)

Macrophage polarization: a key event in the secondary phase of acute spinal cord injury
por: Kong, Xiangyi, et al.
Publicado: (2016)

Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
por: Xue, Meng‐Tong, et al.
Publicado: (2022)

The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis
por: Li, Jing-Lu, et al.
Publicado: (2023)

A Novel Semi‐Cannulated Screw Enhanced Bone Cement Augmentation and Pullout Strength in Posterior Cervical Lateral Mass Screw Fixations: An In Vitro Biomechanical and Morphological Study
por: Canyang, Huang, et al.
Publicado: (2023)

UTX deletion promotes M2 macrophage polarization by epigenetically regulating endothelial cell-macrophage crosstalk after spinal cord injury
por: Peng, Wei, et al.
Publicado: (2023)

Modification of autophagy-lysosomal pathway as a neuroprotective treatment for spinal cord injury
por: Lipinski, Marta M., et al.
Publicado: (2015)

CO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord
por: Zheng, Gang, et al.
Publicado: (2020)

An anti-inflammatory and neuroprotective biomimetic nanoplatform for repairing spinal cord injury
por: Gao, Xiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8o4lsnrlc1qr8j5vrq534imroi