Efficacy of ruxolitinib in a patient with myelodysplastic/myeloproliferative neoplasm unclassifiable and co-mutated JAK2, SF3B1 and TP53

Myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) is a rare but heterogeneous subtype of MDS/MPN, with no specific genetic alterations and standard treatments. ASXL1, SRSF2, TET2, JAK2 and NRAS are commonly mutated in MDS/MPN-U. Double gene mutations could be detected in MDS/MP...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Dai, Hai-ping, Liu, Dan-dan, Xie, Jun-dan, Yao, Hong, Ding, Zi-xuan, Tao, Ting-ting, Chen, Su-ning, Zhang, Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645062/
https://www.ncbi.nlm.nih.gov/pubmed/33194542
http://dx.doi.org/10.1016/j.lrr.2020.100229

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