Cargando…

In Situ Morphologic and Spectral Characterization of Retinal Pigment Epithelium Organelles in Mice Using Multicolor Confocal Fluorescence Imaging

PURPOSE: To investigate the major organelles of the retinal pigment epithelium (RPE) in wild-type (WT, control) mice and their changes in pigmented Abca4 knockout (Abca4(−)(/)(−)) mice with in situ morphologic, spatial, and spectral characterization of live ex vivo flat-mounted RPE using multicolor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meleppat, Ratheesh K., Ronning, Kaitryn E., Karlen, Sarah J., Kothandath, Karuna K., Burns, Marie E., Pugh, Edward N., Zawadzki, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645167/ https://www.ncbi.nlm.nih.gov/pubmed/33137194 http://dx.doi.org/10.1167/iovs.61.13.1

Ejemplares similares

In vivo multimodal retinal imaging of disease-related pigmentary changes in retinal pigment epithelium
por: Meleppat, Ratheesh K., et al.
Publicado: (2021)

Confocal MultiColor Signal Depends on Perfusion Characteristics of Retinal Microaneurysms in Diabetic Retinopathy as Detected by OCTA
por: Arrigo, Alessandro, et al.
Publicado: (2023)

In Vivo Imaging of Retinal and Choroidal Morphology and Vascular Plexuses of Vertebrates Using Swept-Source Optical Coherence Tomography
por: Meleppat, Ratheesh K., et al.
Publicado: (2022)

Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium
por: Meleppat, Ratheesh K., et al.
Publicado: (2019)

Progressive Early Breakdown of Retinal Pigment Epithelium Function in Hyperglycemic Rats
por: Desjardins, Danielle M., et al.
Publicado: (2016)

Associations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments
por: Balaratnasingam, Chandrakumar, et al.
Publicado: (2016)

Function of the Retinal Pigment Epithelium in Patients With Neurofibromatosis Type 1
por: Touzé, Romain, et al.
Publicado: (2022)

Progressive Choriocapillaris Impairment in ABCA4 Maculopathy Is Secondary to Retinal Pigment Epithelium Atrophy
por: Jauregui, Ruben, et al.
Publicado: (2020)

Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis
por: Jiang, Yida, et al.
Publicado: (2022)

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
por: Narendran, Siddharth, et al.
Publicado: (2020)

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration
por: Gambril, J. Alan, et al.
Publicado: (2019)

Progressive Dysmorphia of Retinal Pigment Epithelium in Age-Related Macular Degeneration Investigated by Fluorescence Lifetime Imaging
por: Hammer, Martin, et al.
Publicado: (2021)

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium
por: Cao, Dongfeng, et al.
Publicado: (2021)

Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina
por: Webster, Mark K., et al.
Publicado: (2019)

Histologic Cell Shape Descriptors for the Retinal Pigment Epithelium in Age-Related Macular Degeneration: A Comparison to Unaffected Eyes
por: von der Emde, Leon, et al.
Publicado: (2022)

The Photosensitivity of Rhodopsin Bleaching and Light-Induced Increases of Fundus Reflectance in Mice Measured In Vivo With Scanning Laser Ophthalmoscopy
por: Zhang, Pengfei, et al.
Publicado: (2016)

Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury
por: Xiao, Jianhui, et al.
Publicado: (2017)

Three-Dimensional Characterization of the Normal Human Parafoveal Microvasculature Using Structural Criteria and High-Resolution Confocal Microscopy
por: An, Dong, et al.
Publicado: (2020)

Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) of Macular Pigment
por: Sauer, Lydia, et al.
Publicado: (2018)

Cone Photoreceptor Morphology in Choroideremia Assessed Using Non-Confocal Split-Detection Adaptive Optics Scanning Light Ophthalmoscopy
por: Xu, Peiluo, et al.
Publicado: (2023)

Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
por: Miller, Andrew R., et al.
Publicado: (2017)

Prenatal Carotenoid Supplementation With Lutein or Zeaxanthin Ameliorates Oxygen-Induced Retinopathy (OIR) in Bco2(−/−) Macular Pigment Mice
por: Arunkumar, Ranganathan, et al.
Publicado: (2023)

Local Abundance of Macular Xanthophyll Pigment Is Associated with Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration
por: Kar, Deepayan, et al.
Publicado: (2020)

Quantitative Analysis of Outer Retinal Tubulation in Age-Related Macular Degeneration From Spectral-Domain Optical Coherence Tomography and Histology
por: Litts, Katie M., et al.
Publicado: (2016)

Investigations on Retinal Pigment Epithelial Damage at Laser Irradiation in the Lower Microsecond Time Regime
por: Seifert, Eric, et al.
Publicado: (2021)

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells
por: Spivey, Eric C., et al.
Publicado: (2023)

Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration
por: Ronning, Kaitryn E., et al.
Publicado: (2022)

Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography
por: Ryals, Renee C., et al.
Publicado: (2017)

Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130
por: Wang, Xinlei, et al.
Publicado: (2017)

Grade of Cataract and Its Influence on Measurement of Macular Pigment Optical Density Using Autofluorescence Imaging
por: Obana, Akira, et al.
Publicado: (2018)

Ocular Pigmentation Impact on Retinal Versus Choroidal Optical Coherence Tomography Imaging in Preterm Infants
por: Seely, Kai R., et al.
Publicado: (2023)

Macular Features on Spectral-Domain Optical Coherence Tomography Imaging Associated With Visual Acuity in Coats' Disease
por: Ong, Sally S., et al.
Publicado: (2018)

Temporal speckle-averaging of optical coherence tomography volumes for in-vivo cellular resolution neuronal and vascular retinal imaging
por: Zhang, Pengfei, et al.
Publicado: (2019)

Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Eyes With Pigment Epithelial Detachments Due to Age-Related Macular Degeneration
por: Sauer, Lydia, et al.
Publicado: (2019)

Partial Rescue of Ocular Pigment Cells and Structure by Inducible Ectopic Expression of Mitf-M in MITF-Deficient Mice
por: Michael, Helen T., et al.
Publicado: (2018)

Fluorescence Lifetime and Spectral Characteristics of Subretinal Drusenoid Deposits and Their Predictive Value for Progression of Age-Related Macular Degeneration
por: Weber, Sebastian, et al.
Publicado: (2022)

Radiomics-Based Prediction of Anti-VEGF Treatment Response in Neovascular Age-Related Macular Degeneration With Pigment Epithelial Detachment
por: Williamson, Ryan Chace, et al.
Publicado: (2023)

Bone Marrow–Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy
por: Caballero, Sergio, et al.
Publicado: (2017)

Segmented Macular Layer Volumes from Spectral Domain Optical Coherence Tomography in 184 Adult Twins: Associations With Age and Heritability
por: Lamin, Ali, et al.
Publicado: (2020)

Loss of cone function without degeneration in a novel Gnat2 knock-out mouse
por: Ronning, Kaitryn E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a2o4c97p4rsi71rartldru2kcr