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Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers

β‐arrestins (βarr1 and βarr2) are ubiquitous regulators of G protein‐coupled receptor (GPCR) signaling. Available data suggest that β‐arrestins dock to different receptors in different ways. However, the structural characterization of GPCR‐arrestin complexes is challenging and alternative approaches...

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Detalles Bibliográficos
Autores principales: Böttke, Thore, Ernicke, Stefan, Serfling, Robert, Ihling, Christian, Burda, Edyta, Gurevich, Vsevolod V, Sinz, Andrea, Coin, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645262/
https://www.ncbi.nlm.nih.gov/pubmed/32929862
http://dx.doi.org/10.15252/embr.202050437

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