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Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers
β‐arrestins (βarr1 and βarr2) are ubiquitous regulators of G protein‐coupled receptor (GPCR) signaling. Available data suggest that β‐arrestins dock to different receptors in different ways. However, the structural characterization of GPCR‐arrestin complexes is challenging and alternative approaches...
Autores principales: | Böttke, Thore, Ernicke, Stefan, Serfling, Robert, Ihling, Christian, Burda, Edyta, Gurevich, Vsevolod V, Sinz, Andrea, Coin, Irene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645262/ https://www.ncbi.nlm.nih.gov/pubmed/32929862 http://dx.doi.org/10.15252/embr.202050437 |
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