Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy

Skeletal muscle atrophy with high prevalence can induce weakness and fatigability and place huge burden on both health and quality of life. During skeletal muscle degeneration, excessive fibroblasts and extracellular matrix (ECM) accumulated to replace and impair the resident muscle fiber and led to...

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Detalles Bibliográficos
Autores principales: Chen, Hongtao, Qian, Zhanyang, Zhang, Sheng, Tang, Jian, Fang, Le, Jiang, Fan, Ge, Dawei, Chang, Jie, Cao, Jiang, Yang, Lei, Cao, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645269/
https://www.ncbi.nlm.nih.gov/pubmed/33152664
http://dx.doi.org/10.1016/j.redox.2020.101774

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