Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation

The number of patients with acute episodes of severe bronchospasm needing intubation and ventilatory support has increased rapidly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) pandemic. Although medical consensus upholds the use of venti...

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Autores principales: Salazar, Rafael, Hallo, Alejandro, Vasquez, Sebastian, Reinthaller, Steffy, Echeverria, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645293/
https://www.ncbi.nlm.nih.gov/pubmed/33173630
http://dx.doi.org/10.7759/cureus.10822
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author Salazar, Rafael
Hallo, Alejandro
Vasquez, Sebastian
Reinthaller, Steffy
Echeverria, Juan
author_facet Salazar, Rafael
Hallo, Alejandro
Vasquez, Sebastian
Reinthaller, Steffy
Echeverria, Juan
author_sort Salazar, Rafael
collection PubMed
description The number of patients with acute episodes of severe bronchospasm needing intubation and ventilatory support has increased rapidly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) pandemic. Although medical consensus upholds the use of ventilatory support in this pathology, its survival benefits remain unclear. To improve the outcomes and survival rates, a bundle of early respiratory therapy with a pharmacological rescue regimen was provided to four patients with bronchospasm secondary to COVID-19. This therapeutic approach successfully delayed the need for invasive mechanical ventilation for 48 hours and decreased the mortality rate in all cases.
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spelling pubmed-76452932020-11-09 Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation Salazar, Rafael Hallo, Alejandro Vasquez, Sebastian Reinthaller, Steffy Echeverria, Juan Cureus Emergency Medicine The number of patients with acute episodes of severe bronchospasm needing intubation and ventilatory support has increased rapidly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease 2019 (COVID-19) pandemic. Although medical consensus upholds the use of ventilatory support in this pathology, its survival benefits remain unclear. To improve the outcomes and survival rates, a bundle of early respiratory therapy with a pharmacological rescue regimen was provided to four patients with bronchospasm secondary to COVID-19. This therapeutic approach successfully delayed the need for invasive mechanical ventilation for 48 hours and decreased the mortality rate in all cases. Cureus 2020-10-06 /pmc/articles/PMC7645293/ /pubmed/33173630 http://dx.doi.org/10.7759/cureus.10822 Text en Copyright © 2020, Salazar et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Salazar, Rafael
Hallo, Alejandro
Vasquez, Sebastian
Reinthaller, Steffy
Echeverria, Juan
Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title_full Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title_fullStr Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title_full_unstemmed Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title_short Decreased Mortality in Patients With Severe Bronchospasm Associated With SARS-CoV-2: An Alternative to Invasive Mechanical Ventilation
title_sort decreased mortality in patients with severe bronchospasm associated with sars-cov-2: an alternative to invasive mechanical ventilation
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645293/
https://www.ncbi.nlm.nih.gov/pubmed/33173630
http://dx.doi.org/10.7759/cureus.10822
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