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Klotho deficiency aggravates diabetes-induced podocyte injury due to DNA damage caused by mitochondrial dysfunction

Diabetic nephropathy (DN) is a progressive disease, the main pathogeny of which is podocyte injury inducing glomerular filtration barrier and proteinuria. The occurrence and development of DN could be partly attributed to the reactive oxygen species (ROS) generated by mitochondria. However, research...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Zhou, Qing, Liu, Cong, Zeng, Yiping, Yuan, Shaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645346/
https://www.ncbi.nlm.nih.gov/pubmed/33162804
http://dx.doi.org/10.7150/ijms.49690