Cargando…
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumpt...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645374/ https://www.ncbi.nlm.nih.gov/pubmed/33073919 http://dx.doi.org/10.15252/emmm.202013171 |
_version_ | 1783606643001393152 |
---|---|
author | Loewenthal, Gil Abadi, Shiran Avram, Oren Halabi, Keren Ecker, Noa Nagar, Natan Mayrose, Itay Pupko, Tal |
author_facet | Loewenthal, Gil Abadi, Shiran Avram, Oren Halabi, Keren Ecker, Noa Nagar, Natan Mayrose, Itay Pupko, Tal |
author_sort | Loewenthal, Gil |
collection | PubMed |
description | The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumptions or on official regulations. Here, we use country‐specific reports of daily mobility from people cellular usage to model social distancing. Our data‐driven model enabled the extraction of lockdown characteristics which were crossed with observed mortality rates to show that: (i) the time at which social distancing was initiated is highly correlated with the number of deaths, r (2) = 0.64, while the lockdown strictness or its duration is not as informative; (ii) a delay of 7.49 days in initiating social distancing would double the number of deaths; and (iii) the immediate response has a prolonged effect on COVID‐19 death toll. |
format | Online Article Text |
id | pubmed-7645374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76453742020-11-06 COVID‐19 pandemic‐related lockdown: response time is more important than its strictness Loewenthal, Gil Abadi, Shiran Avram, Oren Halabi, Keren Ecker, Noa Nagar, Natan Mayrose, Itay Pupko, Tal EMBO Mol Med Articles The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumptions or on official regulations. Here, we use country‐specific reports of daily mobility from people cellular usage to model social distancing. Our data‐driven model enabled the extraction of lockdown characteristics which were crossed with observed mortality rates to show that: (i) the time at which social distancing was initiated is highly correlated with the number of deaths, r (2) = 0.64, while the lockdown strictness or its duration is not as informative; (ii) a delay of 7.49 days in initiating social distancing would double the number of deaths; and (iii) the immediate response has a prolonged effect on COVID‐19 death toll. John Wiley and Sons Inc. 2020-10-19 2020-11-06 /pmc/articles/PMC7645374/ /pubmed/33073919 http://dx.doi.org/10.15252/emmm.202013171 Text en © 2020 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Loewenthal, Gil Abadi, Shiran Avram, Oren Halabi, Keren Ecker, Noa Nagar, Natan Mayrose, Itay Pupko, Tal COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title |
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title_full |
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title_fullStr |
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title_full_unstemmed |
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title_short |
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness |
title_sort | covid‐19 pandemic‐related lockdown: response time is more important than its strictness |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645374/ https://www.ncbi.nlm.nih.gov/pubmed/33073919 http://dx.doi.org/10.15252/emmm.202013171 |
work_keys_str_mv | AT loewenthalgil covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT abadishiran covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT avramoren covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT halabikeren covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT eckernoa covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT nagarnatan covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT mayroseitay covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness AT pupkotal covid19pandemicrelatedlockdownresponsetimeismoreimportantthanitsstrictness |