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COVID‐19 pandemic‐related lockdown: response time is more important than its strictness

The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumpt...

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Autores principales: Loewenthal, Gil, Abadi, Shiran, Avram, Oren, Halabi, Keren, Ecker, Noa, Nagar, Natan, Mayrose, Itay, Pupko, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645374/
https://www.ncbi.nlm.nih.gov/pubmed/33073919
http://dx.doi.org/10.15252/emmm.202013171
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author Loewenthal, Gil
Abadi, Shiran
Avram, Oren
Halabi, Keren
Ecker, Noa
Nagar, Natan
Mayrose, Itay
Pupko, Tal
author_facet Loewenthal, Gil
Abadi, Shiran
Avram, Oren
Halabi, Keren
Ecker, Noa
Nagar, Natan
Mayrose, Itay
Pupko, Tal
author_sort Loewenthal, Gil
collection PubMed
description The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumptions or on official regulations. Here, we use country‐specific reports of daily mobility from people cellular usage to model social distancing. Our data‐driven model enabled the extraction of lockdown characteristics which were crossed with observed mortality rates to show that: (i) the time at which social distancing was initiated is highly correlated with the number of deaths, r (2) = 0.64, while the lockdown strictness or its duration is not as informative; (ii) a delay of 7.49 days in initiating social distancing would double the number of deaths; and (iii) the immediate response has a prolonged effect on COVID‐19 death toll.
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spelling pubmed-76453742020-11-06 COVID‐19 pandemic‐related lockdown: response time is more important than its strictness Loewenthal, Gil Abadi, Shiran Avram, Oren Halabi, Keren Ecker, Noa Nagar, Natan Mayrose, Itay Pupko, Tal EMBO Mol Med Articles The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on infection rates. However, these rely on prior assumptions or on official regulations. Here, we use country‐specific reports of daily mobility from people cellular usage to model social distancing. Our data‐driven model enabled the extraction of lockdown characteristics which were crossed with observed mortality rates to show that: (i) the time at which social distancing was initiated is highly correlated with the number of deaths, r (2) = 0.64, while the lockdown strictness or its duration is not as informative; (ii) a delay of 7.49 days in initiating social distancing would double the number of deaths; and (iii) the immediate response has a prolonged effect on COVID‐19 death toll. John Wiley and Sons Inc. 2020-10-19 2020-11-06 /pmc/articles/PMC7645374/ /pubmed/33073919 http://dx.doi.org/10.15252/emmm.202013171 Text en © 2020 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Loewenthal, Gil
Abadi, Shiran
Avram, Oren
Halabi, Keren
Ecker, Noa
Nagar, Natan
Mayrose, Itay
Pupko, Tal
COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title_full COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title_fullStr COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title_full_unstemmed COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title_short COVID‐19 pandemic‐related lockdown: response time is more important than its strictness
title_sort covid‐19 pandemic‐related lockdown: response time is more important than its strictness
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645374/
https://www.ncbi.nlm.nih.gov/pubmed/33073919
http://dx.doi.org/10.15252/emmm.202013171
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