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Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes

Type 1 diabetes arises from the autoimmune destruction of insulin-producing beta-cells of the pancreas, resulting in dependence on exogenously administered insulin to maintain glucose homeostasis. In this study, our aim was to identify genetic risk factors that contribute to progression from islet a...

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Detalles Bibliográficos
Autores principales: Onengut-Gumuscu, Suna, Paila, Umadevi, Chen, Wei-Min, Ratan, Aakrosh, Zhu, Zhennan, Steck, Andrea K., Frohnert, Brigitte I., Waugh, Kathleen C., Webb-Robertson, Bobbie-Jo M., Norris, Jill M., Lange, Leslie A., Rewers, Marian J., Rich, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645414/
https://www.ncbi.nlm.nih.gov/pubmed/33154504
http://dx.doi.org/10.1038/s41598-020-75690-6

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