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Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington’s disease

Huntington’s disease (HD) is a neurodegenerative disorder with a progressive loss of medium spiny neurons in the striatum and aggregation of mutant huntingtin in the striatal and cortical neurons. Currently, there are no rational therapies for the treatment of the disease. Cerebral dopamine neurotro...

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Detalles Bibliográficos
Autores principales: Stepanova, P., Srinivasan, V., Lindholm, D., Voutilainen, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645584/
https://www.ncbi.nlm.nih.gov/pubmed/33154393
http://dx.doi.org/10.1038/s41598-020-75439-1

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