Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution

Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcription in a cell culture model of PEL using single-cell RNA sequencing. The data detect widespread tr...

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Detalles Bibliográficos
Autores principales: Rondeau, Nicole C., Finlayson, Michael O., Miranda, JJ L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Omics Data Sets
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645656/
https://www.ncbi.nlm.nih.gov/pubmed/33154001
http://dx.doi.org/10.1128/MRA.00851-20
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author Rondeau, Nicole C.
Finlayson, Michael O.
Miranda, JJ L.
author_facet Rondeau, Nicole C.
Finlayson, Michael O.
Miranda, JJ L.
author_sort Rondeau, Nicole C.
collection PubMed
description Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcription in a cell culture model of PEL using single-cell RNA sequencing. The data detect widespread trace expression of lytic KSHV genes.
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spelling pubmed-76456562020-11-17 Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution Rondeau, Nicole C. Finlayson, Michael O. Miranda, JJ L. Microbiol Resour Announc Omics Data Sets Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcription in a cell culture model of PEL using single-cell RNA sequencing. The data detect widespread trace expression of lytic KSHV genes. American Society for Microbiology 2020-11-05 /pmc/articles/PMC7645656/ /pubmed/33154001 http://dx.doi.org/10.1128/MRA.00851-20 Text en Copyright © 2020 Rondeau et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Omics Data Sets
Rondeau, Nicole C.
Finlayson, Michael O.
Miranda, JJ L.
Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title_full Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title_fullStr Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title_full_unstemmed Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title_short Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution
title_sort widespread traces of lytic kaposi sarcoma-associated herpesvirus in primary effusion lymphoma at single-cell resolution
topic Omics Data Sets
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645656/
https://www.ncbi.nlm.nih.gov/pubmed/33154001
http://dx.doi.org/10.1128/MRA.00851-20
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