Autofluorescence-based sorting removes senescent cells from mesenchymal stromal cell cultures

Mesenchymal stromal cells (MSC) are used in cell therapy, but results depend on the unknown quality of cell populations. Extended culture time of MSC increases their senescent levels, leading to a critical loss of cell fitness. Here, we tested the suitability of MSC-sorting based on their FACS autof...

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Detalles Bibliográficos
Autores principales: Bertolo, Alessandro, Guerrero, Julien, Stoyanov, Jivko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645702/
https://www.ncbi.nlm.nih.gov/pubmed/33154552
http://dx.doi.org/10.1038/s41598-020-76202-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645702/
https://www.ncbi.nlm.nih.gov/pubmed/33154552
http://dx.doi.org/10.1038/s41598-020-76202-2

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