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Autofluorescence-based sorting removes senescent cells from mesenchymal stromal cell cultures
Mesenchymal stromal cells (MSC) are used in cell therapy, but results depend on the unknown quality of cell populations. Extended culture time of MSC increases their senescent levels, leading to a critical loss of cell fitness. Here, we tested the suitability of MSC-sorting based on their FACS autof...
Autores principales: | Bertolo, Alessandro, Guerrero, Julien, Stoyanov, Jivko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645702/ https://www.ncbi.nlm.nih.gov/pubmed/33154552 http://dx.doi.org/10.1038/s41598-020-76202-2 |
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