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Conserved UBE3A subcellular distribution between human and mice is facilitated by non-homologous isoforms

The human UBE3A gene, which is essential for normal neurodevelopment, encodes three Ubiquitin E3 ligase A (UBE3A) protein isoforms. However, the subcellular localization and relative abundance of these human UBE3A isoforms are unknown. We found, as previously reported in mice, that UBE3A is predomin...

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Detalles Bibliográficos
Autores principales:	Zampeta, F Isabella, Sonzogni, Monica, Niggl, Eva, Lendemeijer, Bas, Smeenk, Hilde, de Vrij, Femke M S, Kushner, Steven A, Distel, Ben, Elgersma, Ype
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645710/ https://www.ncbi.nlm.nih.gov/pubmed/32879944 http://dx.doi.org/10.1093/hmg/ddaa194

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