Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

The membrane-anchored matrix metalloprotease MT1-MMP is a potent collagenolytic enzyme with a well-established role in extracellular matrix turnover and cellular invasion into collagen-rich tissues. MT1-MMP is highly expressed in various types of cancer and has been demonstrated to be directly invol...

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Detalles Bibliográficos
Autores principales: Ingvarsen, Signe Z., Gårdsvoll, Henrik, van Putten, Sander, Nørregaard, Kirstine S., Krigslund, Oliver, Meilstrup, Josephine A., Tran, Collin, Jürgensen, Henrik J., Melander, Maria C., Nielsen, Carsten H., Kjaer, Andreas, Bugge, Thomas H., Engelholm, Lars H., Behrendt, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645741/
https://www.ncbi.nlm.nih.gov/pubmed/33154487
http://dx.doi.org/10.1038/s41598-020-75995-6

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