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Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms
One of the visions of precision medicine has been to re-define disease taxonomies based on molecular characteristics rather than on phenotypic evidence. However, achieving this goal is highly challenging, specifically in neurology. Our contribution is a machine-learning based joint molecular subtypi...
Autores principales: | Emon, Mohammad Asif, Heinson, Ashley, Wu, Ping, Domingo-Fernández, Daniel, Sood, Meemansa, Vrooman, Henri, Corvol, Jean-Christophe, Scordis, Phil, Hofmann-Apitius, Martin, Fröhlich, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645798/ https://www.ncbi.nlm.nih.gov/pubmed/33154531 http://dx.doi.org/10.1038/s41598-020-76200-4 |
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