Cargando…
The role of antifungals in the management of patients with severe asthma
In patients with asthma, the inhalation of elevated amounts of fungal spores and hyphae may precipitate the onset of asthma or worsen control to the extent of being life-threatening. Sensitisation to fungi, especially Aspergillus fumigatus, is found in 15% to 48% of asthmatics in secondary care and...
Autores principales: | Rapeport, W. Garth, Ito, Kazuhiro, Denning, David W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646070/ https://www.ncbi.nlm.nih.gov/pubmed/33292524 http://dx.doi.org/10.1186/s13601-020-00353-8 |
Ejemplares similares
-
In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice
por: Kimura, Genki, et al.
Publicado: (2017) -
Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection
por: Colley, Thomas, et al.
Publicado: (2019) -
In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris
por: Rudramurthy, Shivaprakash M, et al.
Publicado: (2019) -
Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway
por: Coates, Matthew S., et al.
Publicado: (2021) -
Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent
por: Cass, Lindsey, et al.
Publicado: (2020)