Cargando…

Gemcitabine and Selected mTOR Inhibitors in Uterine Sarcomas and Carcinosarcoma Cells- an Isobolographic Analysis

Introduction: mTOR inhibitors are anticancer agents affecting mTOR/AKT/PI3K pathway that is one of the most important in human cancer cells. Hyperactivation of mTOR/AKT/PI3K and overexpression of this pathway members are frequently reported in uterine sarcoma and carcinosarcoma. Present study is aim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bobiński, Marcin, Okła, Karolina, Łuszczki, Jarogniew, Bednarek, Wiesława, Wawruszak, Anna, Moreno-Bueno, Gema, Garcia-Sanz, Pablo, Dmoszyńska-Graniczka, Magdalena, Tarkowski, Rafał, Kotarski, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646097/ https://www.ncbi.nlm.nih.gov/pubmed/33173419 http://dx.doi.org/10.7150/ijms.48187

Ejemplares similares

Isobolographic Analysis Demonstrates the Additive and Synergistic Effects of Gemcitabine Combined with Fucoidan in Uterine Sarcomas and Carcinosarcoma Cells
por: Bobiński, Marcin, et al.
Publicado: (2019)

The Effect of Fucoidan, a Potential New, Natural, Anti-Neoplastic Agent on Uterine Sarcomas and Carcinosarcoma Cell Lines: ENITEC Collaborative Study
por: Bobiński, Marcin, et al.
Publicado: (2019)

Antagonistic Interaction between Histone Deacetylase Inhibitor: Cambinol and Cisplatin—An Isobolographic Analysis in Breast Cancer In Vitro Models
por: Hałasa, Marta, et al.
Publicado: (2021)

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2015)

Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer
por: Okła, Karolina, et al.
Publicado: (2019)

Accumulation of blood-circulating PD-L1-expressing M-MDSCs and monocytes/macrophages in pretreatment ovarian cancer patients is associated with soluble PD-L1
por: Okła, Karolina, et al.
Publicado: (2020)

Correction to: Accumulation of blood-circulating PD-L1-expressing M-MDSCs and monocytes/macrophages in pretreatment ovarian cancer patients is associated with soluble PD-L1
por: Okła, Karolina, et al.
Publicado: (2020)

Antagonistic Pharmacological Interaction between Sirtuin Inhibitor Cambinol and Paclitaxel in Triple-Negative Breast Cancer Cell Lines: An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2022)

Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2019)

Cannabidiol Interacts Antagonistically with Cisplatin and Additively with Mitoxantrone in Various Melanoma Cell Lines—An Isobolographic Analysis
por: Marzęda, Paweł, et al.
Publicado: (2022)

Synergy, Additivity and Antagonism between Esculetin and Six Commonly Used Chemotherapeutics in Various Malignant Melanoma Cell Lines—An Isobolographic Analysis
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2023)

Comparison of the Anticancer Effects of Arvanil and Olvanil When Combined with Cisplatin and Mitoxantrone in Various Melanoma Cell Lines—An Isobolographic Analysis
por: Marzęda, Paweł, et al.
Publicado: (2022)

Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic–clonic seizure model: an isobolographic transformation
por: Łuszczki, Jarogniew J., et al.
Publicado: (2023)

Sub-additive (antagonistic) interaction of lacosamide with lamotrigine and valproate in the maximal electroshock-induced seizure model in mice: an isobolographic analysis
por: Łuszczki, Jarogniew J., et al.
Publicado: (2020)

Fraxetin Interacts Additively with Cisplatin and Mitoxantrone, Antagonistically with Docetaxel in Various Human Melanoma Cell Lines—An Isobolographic Analysis
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2022)

Antiseizure Effects of Scoparone, Borneol and Their Impact on the Anticonvulsant Potency of Four Classic Antiseizure Medications in the Mouse MES Model—An Isobolographic Transformation
por: Łuszczki, Jarogniew J., et al.
Publicado: (2023)

Polygonogram and isobolographic analysis of interactions between various novel antiepileptic drugs in the 6-Hz corneal stimulation-induced seizure model in mice
por: Luszczki, Jarogniew J., et al.
Publicado: (2020)

Polygonogram with isobolographic synergy for three-drug combinations of phenobarbital with second-generation antiepileptic drugs in the tonic–clonic seizure model in mice
por: Łuszczki, Jarogniew J., et al.
Publicado: (2020)

Effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the protective action of various antiepileptic drugs in the maximal electroshock-induced seizure model: a type II isobolographic analysis
por: Andres-Mach, Marta, et al.
Publicado: (2013)

Influence of ovarian cancer type I and type II microenvironment on the phenotype and function of monocyte-derived dendritic cells
por: Surówka, J., et al.
Publicado: (2017)

Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells
por: Grabarska, Aneta, et al.
Publicado: (2017)

Microvessels Density in Uterine Leiomyosarcoma
por: Bobiński, Marcin, et al.
Publicado: (2015)

Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Additive pharmacological interaction between sirtuin inhibitor cambinol and paclitaxel in MCF7 luminal and MDA-MB-231 triple-negative breast cancer cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel
por: Grabarska, Aneta, et al.
Publicado: (2023)

Integration of local and systemic immunity in ovarian cancer: Implications for immunotherapy
por: Rajtak, Alicja, et al.
Publicado: (2022)

The analgesic interaction of tramadol and morphine in rats: An isobolographic study
por: Savadkoohi, Hesam, et al.
Publicado: (2019)

Sensitization of MCF7 Cells with High Notch1 Activity by Cisplatin and Histone Deacetylase Inhibitors Applied Together
por: Wawruszak, Anna, et al.
Publicado: (2021)

Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells
por: Okon, Estera, et al.
Publicado: (2020)

Synergistic or Additive Pharmacological Interactions between Magnoflorine and Cisplatin in Human Cancer Cells of Different Histological Origin
por: Okon, Estera, et al.
Publicado: (2020)

Meigs’ syndrome with elevated CA-125 and HE-4: a case of luteinized fibrothecoma
por: Danilos, Jaroslaw, et al.
Publicado: (2015)

An isobolographic analysis of the antinociceptive effect of xylopic acid in combination with morphine or diclofenac
por: Woode, Eric, et al.
Publicado: (2015)

Ranolazine Interacts Antagonistically with Some Classical Antiepileptic Drugs—An Isobolographic Analysis
por: Borowicz-Reutt, Kinga, et al.
Publicado: (2022)

A rare presentation of carcinosarcoma of the bone in a young female; response with gemcitabine and docetaxel
por: King, Nicholas, et al.
Publicado: (2019)

Interactions of Mexiletine with Novel Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis
por: Wróblewska, Dorota, et al.
Publicado: (2018)

Quantitative Estimation of Synergistic Toxicity of Cu and Zn on Growth of Arabidopsis thaliana by Isobolographic Method
por: Bae, Bumhan, et al.
Publicado: (2022)

Low-Density Lipoproteins Oxidation and Endometriosis
por: Polak, Grzegorz, et al.
Publicado: (2013)

Programmed Death-1 Receptor (PD-1) as a Potential Prognosis Biomarker for Ovarian Cancer Patients
por: Pawłowska, Anna, et al.
Publicado: (2020)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity
por: Lin, Gigin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ifqhf49f8hdnkunvn4sa8107n0