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Metabolic pathways underlying GATA6 regulating Trastuzumab resistance in Gastric Cancer cells based on untargeted metabolomics

Trastuzumab has proven its effectiveness in gastric cancer with HER-2 gene-amplification, which has now developed resistance while the mechanism of which is not fully elucidated. Our previous studies demonstrated that the activity of GATA6 binding protein 6 (GATA6) enhanced prominently in trastuzuma...

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Detalles Bibliográficos
Autores principales: Chang, Jinxia, Wang, Qiang, Bhetuwal, Anup, Liu, Wenhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646115/
https://www.ncbi.nlm.nih.gov/pubmed/33173435
http://dx.doi.org/10.7150/ijms.50563