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IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway

Objectives: This study amied to whether IL-21 promotes osteoblast transdifferentiation of cultured human Valvular interstitial cells (VICs). Methods: We first confirmed that IL-21 alters gene expression between CAVD aortic valve tissue and normal samples by immunohistochemistry, qPCR, and western bl...

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Detalles Bibliográficos
Autores principales:	Liu, Zongtao, Wang, Yixuan, Shi, Jiawei, Chen, Si, Xu, Li, Li, Fei, Dong, Nianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646116/ https://www.ncbi.nlm.nih.gov/pubmed/33173427 http://dx.doi.org/10.7150/ijms.49533

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