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Design and biological evaluation of novel BF-30 analogs for the treatment of malignant melanoma

Aims: To evaluate anti-tumour effects and mechanism of novel BF-30 derivative via cell-based assays and melanoma-bearing model mice. Main methods: BF-30 derivatives were designed by fusing heptapeptide-palmitic tags to native BF-30 via a protease-cleavable linker and prepared by F-moc solid-phase sy...

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Detalles Bibliográficos
Autores principales:	Qi, Jia, Wang, Weiwei, Lu, Wenying, Chen, Wei, Sun, Hui, Shang, Anquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646182/ https://www.ncbi.nlm.nih.gov/pubmed/33193881 http://dx.doi.org/10.7150/jca.47549

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