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Detecting Rare Variants and Heteroplasmy of Mitochondrial DNA from High-Throughput Sequencing in Patients with Coronary Artery Disease

BACKGROUND: Although mutations and dysfunction of mitochondrial DNA (mtDNA) are related to a variety of diseases, few studies have focused on the relationship between mtDNA and coronary artery disease (CAD), especially the relationship between rare variants and CAD. MATERIAL/METHODS: Two-stage high-...

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Detalles Bibliográficos
Autores principales: Jia, Qian, Xu, Lu, Shen, Juan, Wei, Yanping, Xu, Huaiqian, Shi, Jionglong, Jia, Zhilong, Zhao, Xiaojing, Liu, Chunlei, Zhong, Qin, Tian, Yaping, He, Kunlun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646198/
https://www.ncbi.nlm.nih.gov/pubmed/33132382
http://dx.doi.org/10.12659/MSM.925401