Cargando…

Detecting Rare Variants and Heteroplasmy of Mitochondrial DNA from High-Throughput Sequencing in Patients with Coronary Artery Disease

BACKGROUND: Although mutations and dysfunction of mitochondrial DNA (mtDNA) are related to a variety of diseases, few studies have focused on the relationship between mtDNA and coronary artery disease (CAD), especially the relationship between rare variants and CAD. MATERIAL/METHODS: Two-stage high-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Qian, Xu, Lu, Shen, Juan, Wei, Yanping, Xu, Huaiqian, Shi, Jionglong, Jia, Zhilong, Zhao, Xiaojing, Liu, Chunlei, Zhong, Qin, Tian, Yaping, He, Kunlun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646198/ https://www.ncbi.nlm.nih.gov/pubmed/33132382 http://dx.doi.org/10.12659/MSM.925401

Ejemplares similares

Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms
por: Ma, Yanping, et al.
Publicado: (2017)

Effects of Simazine Exposure on Neuronal Development-Related Factors in MN9D Cells
por: Yu, Jia, et al.
Publicado: (2016)

Metformin Enhances Functional Recovery of Peripheral Nerve in Rats with Sciatic Nerve Crush Injury
por: Liu, Lei, et al.
Publicado: (2019)

Immune Response of Plasmacytoid Dendritic Cells Stimulated by Human Papillomavirus (HPV) E6 in an In Vitro System
por: Xu, Xiaoxian, et al.
Publicado: (2020)

Dexmedetomidine Attenuates Glutamate-Induced Cytotoxicity by Inhibiting the Mitochondrial-Mediated Apoptotic Pathway
por: Zhang, Weidong, et al.
Publicado: (2020)

Knockdown of Long Noncoding RNA (lncRNA) AK094457 Relieved Angiotensin II Induced Vascular Endothelial Cell Injury
por: Xu, JiaYi, et al.
Publicado: (2020)

Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Activated Protein Kinase (MAPK) and PI3K/AKT Signaling Pathways
por: Luo, Guoqing, et al.
Publicado: (2019)

Lipid Biomarkers in Acute Myocardial Infarction Before and After Percutaneous Coronary Intervention by Lipidomics Analysis
por: Feng, Limin, et al.
Publicado: (2018)

Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway
por: Fang, Kaifeng, et al.
Publicado: (2019)

High-Throughput Sequencing Strategy for miR-146b-regulated circRNA Expression in Hepatic Stellate Cells
por: Cheng, Na, et al.
Publicado: (2018)

Obestatin Plays Beneficial Role in Cardiomyocyte Injury Induced by Ischemia-Reperfusion In Vivo and In Vitro
por: Zhang, Qin, et al.
Publicado: (2017)

Antitumor Effects of Glychionide-A Flavonoid in Human Pancreatic Carcinoma Cells Are Mediated by Activation of Apoptotic and Autophagic Pathways, Cell Cycle Arrest, and Disruption of Mitochondrial Membrane Potential
por: Yu, Lei, et al.
Publicado: (2019)

Anti-Tumor Effects of Paeoniflorin on Epithelial-To-Mesenchymal Transition in Human Colorectal Cancer Cells
por: Zhang, Jia-Wei, et al.
Publicado: (2018)

Effect of ANGPTL7 on Proliferation and Differentiation of MC3T3-E1 Cells
por: Lu, XiaoQing, et al.
Publicado: (2019)

Mean Corpuscular Volume Predicts In-Stent Restenosis Risk for Stable Coronary Artery Disease Patients Receiving Elective Percutaneous Coronary Intervention
por: Sun, Lin, et al.
Publicado: (2019)

Oxidized Low Density Lipoprotein-Induced Atherogenic Response of Human Umbilical Vascular Endothelial Cells (HUVECs) was Protected by Atorvastatin by Regulating miR-26a-5p/Phosphatase and Tensin Homolog (PTEN)
por: Jia, Zhuowen, et al.
Publicado: (2019)

Bidirectional Regulatory Effects of Dexmedetomidine on Porcine Coronary Tone In Vitro
por: Zhou, Shu-Zhi, et al.
Publicado: (2017)

Effects of Connexin43 Overexpression on U251 Cell Growth, Migration, and Apoptosis
por: Lu, Jia, et al.
Publicado: (2017)

Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer
por: Meng, Yingying, et al.
Publicado: (2020)

Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells
por: Li, Xiaomeng, et al.
Publicado: (2021)

Downregulation of MiR-218-5p Protects Against Oxygen-Glucose Deprivation/Reperfusion-Induced Injuries of PC12 Cells via Upregulating N-myc Downstream Regulated Gene 4 (NDRG4)
por: Zhu, Huiying, et al.
Publicado: (2020)

Induction of Apoptosis in Lung Cancer Cells by Viburnum grandiflorum via Mitochondrial Pathway
por: Han, Bing, et al.
Publicado: (2020)

Association of Single-Nucleotide Polymorphisms of CD44 Gene with Susceptibility to Breast Cancer in Chinese Women
por: Lin, Xiao, et al.
Publicado: (2018)

Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy
por: Tan, Qian, et al.
Publicado: (2017)

Two GEO MicroRNA Expression Profile Based High-Throughput Screen to Identify MicroRNA-31-3p Regulating Growth of Medullary Thyroid Carcinoma Cell by Targeting RASA2
por: Jiang, Mei, et al.
Publicado: (2019)

High Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Expression Promotes Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer via ERK/Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway
por: Liu, Chang, et al.
Publicado: (2019)

Overexpression of E74-Like Factor 5 (ELF5) Inhibits Migration and Invasion of Ovarian Cancer Cells
por: Zhang, Xiaofeng, et al.
Publicado: (2019)

Comprehensive Bioinformatics Analysis of the Immune Mechanism of Dendritic Cells Against Measles Virus
por: Jia, Lili, et al.
Publicado: (2019)

Long Noncoding RNA LINC01125 Enhances Cisplatin Sensitivity of Ovarian Cancer via miR-1972
por: Guo, Jia, et al.
Publicado: (2019)

Association Between Oxidative Stress and Peripheral Leukocyte Telomere Length in Patients with Premature Coronary Artery Disease
por: Tian, Ran, et al.
Publicado: (2017)

Altered Mitochondrial Dynamics, Biogenesis, and Functions in the Paclitaxel-Resistant Lung Adenocarcinoma Cell Line A549/Taxol
por: Zhou, Xiang, et al.
Publicado: (2020)

Interleukin-22 Promotes Osteosarcoma Cell Proliferation and Invasion via STAT3 Activation
por: Li, Panpan, et al.
Publicado: (2018)

Long Non-Coding RNA (lncRNA) CRNDE Regulated Lipopolysaccharides (LPS)-Induced MRC-5 Inflammation Injury Through Targeting MiR-141
por: Tang, Xingping, et al.
Publicado: (2020)

miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1)
por: Wang, Jia, et al.
Publicado: (2018)

Dexmedetomidine Regulates Proliferation, Apoptosis, Migration, and Invasion in Ovarian Cancer Cells via MiR-155-HIF-1α Axis
por: Zheng, Lihong, et al.
Publicado: (2019)

Establishment of the Prognosis Predicting Signature for Endometrial Cancer Patient
por: Tang, Jia, et al.
Publicado: (2019)

MiR-206 Suppresses the Progression of Coronary Artery Disease by Modulating Vascular Endothelial Growth Factor (VEGF) Expression
por: Wang, Maojing, et al.
Publicado: (2016)

IKBKE Upregulation is Positively Associated with Squamous Cell Carcinoma of the Lung In Vivo and Malignant Transformation of Human Bronchial Epithelial Cells In Vitro
por: Li, Wei, et al.
Publicado: (2015)

Does Use of Lidocaine Affect Culture of Synovial Fluid Obtained to Diagnose Periprosthetic Joint Infection (PJI)? An In Vitro Study
por: Liu, Kan, et al.
Publicado: (2018)

Punicalagin Exerts Beneficial Functions in 6-Hydroxydopamine-Treated SH-SY5Y Cells by Attenuating Mitochondrial Dysfunction and Inflammatory Responses
por: Chu, Jianfeng, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d4alpunkkckt1vr6otvkvfj01r