A 22-amino-acid peptide regulates tight junctions through occludin and cell apoptosis

Occludin is a structural protein of tight junctions (TJ) in the blood–testis barrier (BTB). A 22-amino-acid peptide (22AA) in the second extracellular loop can reversibly regulate TJ, but its regulatory mechanism is unknown. In this study, a 22AA-induced TJ destruction animal model was constructed t...

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Detalles Bibliográficos
Autores principales: Zhu, Maoying, Lu, Juan, Shen, Jianyun, Fei, Lumin, Chen, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646304/
https://www.ncbi.nlm.nih.gov/pubmed/33194394
http://dx.doi.org/10.7717/peerj.10147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646304/
https://www.ncbi.nlm.nih.gov/pubmed/33194394
http://dx.doi.org/10.7717/peerj.10147

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