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A 22-amino-acid peptide regulates tight junctions through occludin and cell apoptosis
Occludin is a structural protein of tight junctions (TJ) in the blood–testis barrier (BTB). A 22-amino-acid peptide (22AA) in the second extracellular loop can reversibly regulate TJ, but its regulatory mechanism is unknown. In this study, a 22AA-induced TJ destruction animal model was constructed t...
Autores principales: | Zhu, Maoying, Lu, Juan, Shen, Jianyun, Fei, Lumin, Chen, Deyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646304/ https://www.ncbi.nlm.nih.gov/pubmed/33194394 http://dx.doi.org/10.7717/peerj.10147 |
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