Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice

BACKGROUND: Treatments for pancreatic ductal adenocarcinoma are poorly effective, at least partly due to the tumor’s immune-suppressive stromal compartment. New evidence of positive effects on immune responses in the tumor microenvironment (TME), compelled us to test the combination of gemcitabine (...

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Detalles Bibliográficos
Autores principales: Selvanesan, Benson Chellakkan, Meena, Kiran, Beck, Amanda, Meheus, Lydie, Lara, Olaya, Rooman, Ilse, Gravekamp, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646363/
https://www.ncbi.nlm.nih.gov/pubmed/33154149
http://dx.doi.org/10.1136/jitc-2020-001250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646363/
https://www.ncbi.nlm.nih.gov/pubmed/33154149
http://dx.doi.org/10.1136/jitc-2020-001250

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