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A Novel MYH9-RET Fusion Occurrence and EGFR T790M Loss as an Acquired Resistance Mechanism to Osimertinib in a Patient with Lung Adenocarcinoma: A Case Report

BACKGROUND: Osimertinib is a novel and irreversible epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) targeting EGFR sensitive mutations and EGFR exon20 p.T790M mutation, which demonstrated superior progression-free survival (PFS) and overall survival (OS). CASE PRESENTATION: W...

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Detalles Bibliográficos
Autores principales:	Sun, Yanwei, Pei, Lina, Luo, Ningning, Chen, Dongsheng, Meng, Lingxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646409/ https://www.ncbi.nlm.nih.gov/pubmed/33173309 http://dx.doi.org/10.2147/OTT.S267524

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