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Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization-associated cell death

The proton pump inhibitor lansoprazole (LPZ) inhibits the growth of several cancer cell lines, including A549 and CAL 27. We previously reported that macrolide antibiotics such as azithromycin (AZM) and clarithromycin (CAM) potently inhibit autophagic flux and that combining AZM or CAM with the epid...

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Detalles Bibliográficos
Autores principales:	Takeda, Atsuo, Takano, Naoharu, Kokuba, Hiroko, Hino, Hirotsugu, Moriya, Shota, Abe, Akihisa, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646592/ https://www.ncbi.nlm.nih.gov/pubmed/33173988 http://dx.doi.org/10.3892/ijo.2020.5138

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