Pancreatic Ductal Adenocarcinoma: Characteristics of Tumor Microenvironment and Barriers to Treatment

Pancreatic ductal adenocarcinoma remains a highly aggressive disease, with a 5-year relative survival rate of 10%. Numerous barriers to treatment exist, such as dense desmoplasia, infiltration of immune suppressor cells, inhibitory cytokines, low effector T-cell infiltration, and low tumor mutationa...

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Detalles Bibliográficos
Autores principales: Kane, Sujata, Engelhart, Anne, Guadagno, Jessica, Jones, Aaron, Usoro, Innis, Brutcher, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Harborside Press LLC 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646635/
https://www.ncbi.nlm.nih.gov/pubmed/33575066
http://dx.doi.org/10.6004/jadpro.2020.11.7.4

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