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A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection

OBJECTIVE AND DESIGN: A randomized, open-label pilot study in individuals treated with antiretroviral therapy (ART) since acute HIV infection (AHI) with a regimen including a histone deacetylase inhibitor to induce HIV from latency and control HIV replication during subsequent treatment interruption...

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Detalles Bibliográficos
Autores principales: Kroon, Eugène D.M.B., Ananworanich, Jintanat, Pagliuzza, Amélie, Rhodes, Ajantha, Phanuphak, Nittaya, Trautmann, Lydie, Mitchell, Julie L., Chintanaphol, Michelle, Intasan, Jintana, Pinyakorn, Suteeraporn, Benjapornpong, Khuntalee, Chang, J. Judy, Colby, Donn J., Chomchey, Nitiya, Fletcher, James L.K., Eubanks, Keith, Yang, Hua, Kapson, John, Dantanarayana, Ashanti, Tennakoon, Surekha, Gorelick, Robert J., Maldarelli, Frank, Robb, Merlin L., Kim, Jerome H., Spudich, Serena, Chomont, Nicolas, Phanuphak, Praphan, Lewin, Sharon R., de Souza, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646672/
https://www.ncbi.nlm.nih.gov/pubmed/33251022
http://dx.doi.org/10.1016/j.jve.2020.100004