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Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis

PURPOSE: The purpose of this study was to compare the rates of success, relapse, and compliance to treatment in patients undergoing alarm therapy or receiving desmopressin for primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS: This retrospective study was performed by reviewin...

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Autores principales: Cakiroglu, Basri, Arda, Ersa, Tas, Tuncay, Senturk, Aykut Bugra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646679/
https://www.ncbi.nlm.nih.gov/pubmed/32769363
http://dx.doi.org/10.4103/ajps.AJPS_115_16
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author Cakiroglu, Basri
Arda, Ersa
Tas, Tuncay
Senturk, Aykut Bugra
author_facet Cakiroglu, Basri
Arda, Ersa
Tas, Tuncay
Senturk, Aykut Bugra
author_sort Cakiroglu, Basri
collection PubMed
description PURPOSE: The purpose of this study was to compare the rates of success, relapse, and compliance to treatment in patients undergoing alarm therapy or receiving desmopressin for primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS: This retrospective study was performed by reviewing the medical files of patients undergoing alarm therapy (Group 1) or receiving desmopressin (Group 2) for PMNE, between January 2010 and July 2014. Patients undergoing treatment in the 3(rd) and 6(th) month as well as 1(st) year follow-up data were analyzed. Two groups were compared with regard to treatment success, relapse rate, and compliance to treatment. RESULTS: Group 1 included 64 and Group 2 included 70 children. Relapse rates at the 3(rd) month, 6(th) month, and 1(st) year were 67.2%, 71.9%, and 17.0% for Group 1 and 74.3%, 80.0%, and 21.4% for Group 2, respectively. There was no statistically significant difference between relapse rates at any point of follow-up. CONCLUSIONS: Alarm therapy and desmopressin have the same success rate and relapse rates for PMNE. Compliance with alarm therapy is higher and we recommend it as the first-line treatment. On the other hand, desmopressin has low side effects and can also be used.
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spelling pubmed-76466792020-11-13 Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis Cakiroglu, Basri Arda, Ersa Tas, Tuncay Senturk, Aykut Bugra Afr J Paediatr Surg Original Article PURPOSE: The purpose of this study was to compare the rates of success, relapse, and compliance to treatment in patients undergoing alarm therapy or receiving desmopressin for primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS: This retrospective study was performed by reviewing the medical files of patients undergoing alarm therapy (Group 1) or receiving desmopressin (Group 2) for PMNE, between January 2010 and July 2014. Patients undergoing treatment in the 3(rd) and 6(th) month as well as 1(st) year follow-up data were analyzed. Two groups were compared with regard to treatment success, relapse rate, and compliance to treatment. RESULTS: Group 1 included 64 and Group 2 included 70 children. Relapse rates at the 3(rd) month, 6(th) month, and 1(st) year were 67.2%, 71.9%, and 17.0% for Group 1 and 74.3%, 80.0%, and 21.4% for Group 2, respectively. There was no statistically significant difference between relapse rates at any point of follow-up. CONCLUSIONS: Alarm therapy and desmopressin have the same success rate and relapse rates for PMNE. Compliance with alarm therapy is higher and we recommend it as the first-line treatment. On the other hand, desmopressin has low side effects and can also be used. Wolters Kluwer - Medknow 2018 2020-08-05 /pmc/articles/PMC7646679/ /pubmed/32769363 http://dx.doi.org/10.4103/ajps.AJPS_115_16 Text en Copyright: © 2020 African Journal of Paediatric Surgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Cakiroglu, Basri
Arda, Ersa
Tas, Tuncay
Senturk, Aykut Bugra
Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title_full Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title_fullStr Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title_full_unstemmed Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title_short Alarm Therapy and Desmopressin in the Treatment of Patients with Nocturnal Enuresis
title_sort alarm therapy and desmopressin in the treatment of patients with nocturnal enuresis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646679/
https://www.ncbi.nlm.nih.gov/pubmed/32769363
http://dx.doi.org/10.4103/ajps.AJPS_115_16
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