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Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis

Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possib...

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Autores principales: Mukherjee, Aveek, Ghosh, Raisa, Furment, Marlene Marte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646749/
https://www.ncbi.nlm.nih.gov/pubmed/32918409
http://dx.doi.org/10.4269/ajtmh.20-0869
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author Mukherjee, Aveek
Ghosh, Raisa
Furment, Marlene Marte
author_facet Mukherjee, Aveek
Ghosh, Raisa
Furment, Marlene Marte
author_sort Mukherjee, Aveek
collection PubMed
description Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possible hepatic damage and tissue tropism of the virus. This leads to frequent pulmonary and cerebral thromboembolism as well as occasional involvement of other organs. We present a 71-year-old man who initially presented with 2 weeks of fever, cough, and shortness of breath and was diagnosed with COVID-19 pneumonia. He required readmission due to worsened hypoxia and was later found to have left renal artery thrombosis with left kidney infarction, associated with an ascending aortic thrombus. He was anticoagulated and recovered uneventfully. We suggest that physicians have a high degree of suspicion to diagnose and manage the novel manifestations of this disease.
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spelling pubmed-76467492020-11-17 Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis Mukherjee, Aveek Ghosh, Raisa Furment, Marlene Marte Am J Trop Med Hyg Articles Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possible hepatic damage and tissue tropism of the virus. This leads to frequent pulmonary and cerebral thromboembolism as well as occasional involvement of other organs. We present a 71-year-old man who initially presented with 2 weeks of fever, cough, and shortness of breath and was diagnosed with COVID-19 pneumonia. He required readmission due to worsened hypoxia and was later found to have left renal artery thrombosis with left kidney infarction, associated with an ascending aortic thrombus. He was anticoagulated and recovered uneventfully. We suggest that physicians have a high degree of suspicion to diagnose and manage the novel manifestations of this disease. The American Society of Tropical Medicine and Hygiene 2020-11 2020-09-10 /pmc/articles/PMC7646749/ /pubmed/32918409 http://dx.doi.org/10.4269/ajtmh.20-0869 Text en © The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Articles
Mukherjee, Aveek
Ghosh, Raisa
Furment, Marlene Marte
Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title_full Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title_fullStr Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title_full_unstemmed Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title_short Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
title_sort case report: covid-19 associated renal infarction and ascending aortic thrombosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646749/
https://www.ncbi.nlm.nih.gov/pubmed/32918409
http://dx.doi.org/10.4269/ajtmh.20-0869
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